Alam Kiran, Jain Anshu, Maheshwari Veena, Siddiqui Farhan Asif, Haider Nazima, Khan Arshad Hafiz
Department of Pathology, JN Medical College, Aligarh Muslim University, Aligarh.
Diagn Cytopathol. 2011 Jun;39(6):461-7. doi: 10.1002/dc.21447. Epub 2010 Sep 20.
To establish the role of fine-needle aspiration cytology (FNAC) as a diagnostic tool for non-Hodgkins lymphoma in a resource challenged environment. This study was conducted on patients with lymphadenopathy, attending various clinics over a period of 18 months. FNAC of the enlarged lymph nodes was performed and biopsy, special stains and immunohistochemical staining was done in selected cases. Out of the total 275 cases, 42 cases (16%) were primary lymphoproliferative disorders. Non-Hodgkin lymphoma comprised of 32 cases (76.2% of all lymphomas), Hodgkin lymphoma-10 cases and the rest were metastatic carcinoma. The diagnostic accuracy for non-Hodgkin Lymphoma was 93.3%, sensitivity 95.4%, and specificity 87.5%. FNAC is a rapid, safe, easy, and nonexpensive diagnostic technique which can be used for early diagnosis of non-Hodgkins lymphoma.
在资源有限的环境中确立细针穿刺细胞学检查（FNAC）作为非霍奇金淋巴瘤诊断工具的作用。本研究针对在18个月期间到各个诊所就诊的淋巴结病患者进行。对肿大的淋巴结进行了FNAC检查，并在部分病例中进行了活检、特殊染色和免疫组织化学染色。在总共275例病例中，42例（16%）为原发性淋巴增殖性疾病。非霍奇金淋巴瘤包括32例（占所有淋巴瘤的76.2%），霍奇金淋巴瘤10例，其余为转移性癌。非霍奇金淋巴瘤的诊断准确率为93.3%，敏感性为95.4%，特异性为87.5%。FNAC是一种快速、安全、简便且经济的诊断技术，可用于非霍奇金淋巴瘤的早期诊断。
