Ogbemudia A O, Bafor A, Edomwonyi E, Enemudo R
Department of Surgery, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.
Niger J Clin Pract. 2010 Sep;13(3):268-71.
Infection at the pin tract is a common complication of external fixation. This study was done to compare the rate of pin site infection following combined 1% silver sulphadiazine and 5 % chlorbexidine dressing with 5% chlorhexidine dressing alone.
This was a prospective controlled study which compared the results of pin site dressing using a combination of chlorhexidine and silver sulphadiazine cream (Study group) with dressing using chlorhexidine alone. Eligible patients had external fixation in the treatment of open fractures or orthopaedic conditions. Pin-tract infection was deemed to be present iferythema, cellulitis or purulent discharge occurred around a pin site. We did not distinguish between deep and superficial infection.
The study group had one hundred and seventy pin sites while the control group had one hundred and sixty-four pin sites. Thirty-eight patients, in whom thirty-seven uniplanar external fixators and one Ilizarov ring fixator were used, made up both groups. Three patients (7.9%) had pin tract infection in the study group while nine patients (23.7%) had pin tract infection in the control group.
There was a significantly lower prevalence of pin-tract infection amongst patients whose external fixation pins were dressed with 1% silver sulphadiazine and 5% chlorhexidine than in those dressed with chlorhexidine alone (P = 0.03). Therefore, we advocate the use of a combination of silver sulphadiazine and chlorhexidine for pin site dressing.
针道感染是外固定的常见并发症。本研究旨在比较联合使用1%磺胺嘧啶银和5%氯己定敷料与单独使用5%氯己定敷料后的针道感染率。
这是一项前瞻性对照研究,比较了使用氯己定和磺胺嘧啶银乳膏联合进行针道换药的结果(研究组)与单独使用氯己定换药的结果。符合条件的患者在治疗开放性骨折或骨科疾病时采用了外固定。如果针道周围出现红斑、蜂窝织炎或脓性分泌物,则视为存在针道感染。我们没有区分深部感染和浅表感染。
研究组有170个针道,对照组有164个针道。两组共有38例患者,其中使用了37个单平面外固定器和1个伊里扎洛夫环形固定器。研究组有3例患者(7.9%)发生针道感染,而对照组有9例患者(23.7%)发生针道感染。
外固定针使用1%磺胺嘧啶银和5%氯己定换药的患者针道感染发生率明显低于单独使用氯己定换药的患者(P = 0.03)。因此,我们提倡使用磺胺嘧啶银和氯己定联合进行针道换药。