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玻璃体内注射雷珠单抗(Lucentis®)治疗点状内层脉络膜病变继发的脉络膜新生血管膜

[Intravitreal ranibizumab (Lucentis®) in the treatment of choroidal neovascular membrane secondary to punctate inner choroidopathy].

作者信息

Valverde Megías A, Arriola Villalobos P, Reche Frutos J, Donate López J, Calvo González C, García Feijoo J

机构信息

Licenciatura en Medicina, Unidad de Patología Macular, Hospital Clínico San Carlos, Madrid, España.

出版信息

Arch Soc Esp Oftalmol. 2010 Apr;85(4):149-52.

Abstract

CLINIC CASE

A 25 year old patient with high myopia diagnosed of metachronic choroidal neovascularisation in both eyes secondary to punctate inner choroidopathy leading to visual impairment and metamorphopsia. First eye was treated with four injections of ranibizumab after photodynamic therapy and the second eye only with charge dose of ranibizumab, reaching inactivity with good final visual acuity in both eyes.

DISCUSSION

Ranibizumab is useful in the treatment of this illness. Prospective studies are needed to investigate the usefulness of a combination with adjuvant therapies such as photodynamic therapy.

摘要

临床病例

一名25岁高度近视患者,双眼诊断为点状内层脉络膜病变继发的陈旧性脉络膜新生血管形成,导致视力损害和视物变形。第一只眼在光动力治疗后接受了4次雷珠单抗注射,第二只眼仅接受了负荷剂量的雷珠单抗治疗,双眼最终均达到静止状态且视力良好。

讨论

雷珠单抗对本病治疗有效。需要进行前瞻性研究以探讨其与光动力治疗等辅助治疗联合使用的有效性。

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