Damm C, Degen H, Stoepel C, Haude M
Medizinische Klinik I, Lukas Krankenhaus Neuss.
Dtsch Med Wochenschr. 2010 Oct;135(39):1914-7. doi: 10.1055/s-0030-1263338. Epub 2010 Sep 21.
A 72-year-old woman presented with progressive dyspnea on exertion. There was no chest pain. A 4/6 systolic murmur was detected on auscultation.
Echocardiography demonstrated a combined aortic valve defect with severe stenosis and moderate insufficiency, additionally a persistent foramen ovale. The coronary angiography revealed coronary heart disease with severe stenosis of the left anterior descending (LAD) and the right coronary artery (RCA). The stenosis of the aortic valve was severe (Pmax 91 mm Hg, Pmean 52 mm Hg). During catheterization of the right heart iatrogenic perforation of a pulmonary artery occurred, resulting in diffuse pulmonary bleeding. The patient suffered from progredient dyspnea and hemoptysis.
DIAGNOSIS, TREATMENT AND COURSE: Catheter-induced rupture of an artery of the right inferior pulmonary lobe was diagnosed. Because of bleeding into this lobe an immediate intubation with a double-lumen bronchial tube was necessary to ensure ventilation of the contralateral lung. Several attempts to occlude the arterial leak by ballon failed. Bleeding stopped after embolisation of the vessel by injection of thrombin.
Iatrogenic rupture of a pulmonary artery is a rare and life-threatening complication of the catheterization of the right heart and demands rapid therapy. The protection of the contralateral lung by intubation with a double-lumen tubes is of highest priority. Selective embolization of the affected vessel via thrombin can be a lifesaving alternative to lobectomy or conservative therapy.
一名72岁女性因进行性劳力性呼吸困难就诊。无胸痛症状。听诊发现有4/6级收缩期杂音。
超声心动图显示主动脉瓣联合缺损,伴有严重狭窄和中度关闭不全,此外还有持续存在的卵圆孔未闭。冠状动脉造影显示冠心病,左前降支(LAD)和右冠状动脉(RCA)严重狭窄。主动脉瓣狭窄严重(峰值压差91 mmHg,平均压差52 mmHg)。在右心导管检查过程中发生了医源性肺动脉穿孔,导致弥漫性肺出血。患者出现进行性呼吸困难和咯血。
诊断、治疗及病程:诊断为导管诱发的右下肺叶动脉破裂。由于该肺叶出血,需要立即插入双腔支气管导管以确保对侧肺通气。多次尝试用球囊封堵动脉漏血均失败。注入凝血酶对血管进行栓塞后出血停止。
医源性肺动脉破裂是右心导管检查罕见且危及生命的并发症,需要迅速治疗。通过插入双腔管保护对侧肺是首要任务。经凝血酶对受累血管进行选择性栓塞可作为肺叶切除术或保守治疗的挽救生命的替代方法。