Huang Z P, Liang K H
Department of Medicine, Tongji Hospital, Tongji Medical University, Wuhan.
Zhonghua Nei Ke Za Zhi. 1990 Aug;29(8):461-4, 509.
To explore a definite diagnostic criterion of chronic gastritis, we undertook a quantitative study of the gastric biopsy specimens taken from 131 subjects. Seven stages were classified from normal gastric mucosa to mild, moderate and severe superficial and atrophic gastritis. The results shown the number of inflammatory cell was much greater in the mild superficial gastritis (128 +/- 84.37/HP) than in normal gastric mucosa (22 +/- 10.54HP, P less than 0.001). In these stages, the numbers of pyloric and fundic gland progressively decreased, the size of the gastric gland gradually enlarged and the percentage of intestinal metaplasia by degrees increased. According to these, we establish the quantitative diagnostic criterion of chronic gastritis.
为探索慢性胃炎的明确诊断标准,我们对131例受试者的胃活检标本进行了定量研究。从正常胃黏膜到轻度、中度和重度浅表性及萎缩性胃炎共分为七个阶段。结果显示,轻度浅表性胃炎的炎症细胞数量(128±84.37/HP)比正常胃黏膜(22±10.54/HP,P<0.001)多得多。在这些阶段中,幽门腺和胃底腺数量逐渐减少,胃腺大小逐渐增大,肠化生百分比逐渐增加。据此,我们建立了慢性胃炎的定量诊断标准。