Georgiev A, Dikova R, Sivchev S
Vutr Boles. 1982;21(4):14-22.
The objective of the paper is the specification of morphological criteria for the diagnostics of chronic gastritis. Biopsies, taken from the antral and corporal mucosa of 317 patients, were studied. Light chronic superficial gastritis was established in 184 cases. Manifested chronic superficial gastritis--in 178 cases, 119 of them in the antrum. Chronic gastritis with initial atrophy of the glands was established in II cases, and complete--in one. Chronic gastritis with intestinal metaplasia was observed in the antral mucosa mainly, and with various degrees of glandular atrophy both in case of the chronic superficial gastritis and chronic gastritis. The chronic gastritis with some changes in the glands, but without atrophy--47 cases, is of particular interest. The intestinal metaplasia as well as the pylorization of the corporal glands in chronic gastritis with changes in the glands without atrophy are a manifestation of dysregeneratory disorders and disturbance in the coordination between the phases of proliferation and differentiation.
本文的目的是明确慢性胃炎诊断的形态学标准。对317例患者胃窦和胃体黏膜活检标本进行了研究。确诊为轻度慢性浅表性胃炎的有184例。显性慢性浅表性胃炎178例，其中119例位于胃窦。确诊为腺体初期萎缩性慢性胃炎的有11例，完全萎缩性的1例。肠化生型慢性胃炎主要见于胃窦黏膜，在慢性浅表性胃炎和慢性胃炎病例中均伴有不同程度的腺体萎缩。腺体有某些改变但无萎缩的慢性胃炎47例，尤其值得关注。在腺体有改变但无萎缩的慢性胃炎中，肠化生以及胃体腺体幽门腺化生是再生调节障碍以及增殖与分化阶段协调紊乱的表现。
