Li Guang-xue, Guo Wei, Tang Shun, Li Xiao, Qi Dian-wen
Musculoskeletal Tumor Center, Peking University of People's Hospital, Beijing 100044, China.
Zhongguo Gu Shang. 2010 Aug;23(8):629-31.
To study the clinical features and surgical treatment of osteoid osteoma and improve the diagnostic therapeutic level.
Clinical data of 35 patients (25 males and 10 females) with osteoid osteoma diagnosed and treated between January 1997 to October 2009 were retrospectively reviewed. The average age was 21 years (ranged, 6 to 49 years). The average interval time between onset of symptoms and diagnosis was 12 months (ranged, 1 to 24 months). The most common sites were the tibia (13 patients) and the femurs (7 patients). The most common presenting complaints for patients with osteoid osteoma was pain which usually responded to NSAIDs and was generally more severe at night. The imaging manifestations revealed a circular or oval nidus. All the patients underwent surgical treatment. The tumors were treated with curettage or excision with autograft or allograft in 19 patients, simple surgical resection in 9 patients, curettage or excision with autograft or allograft and fixation in 7 patients.
The mean follow-up period was 49 months (ranged,2 months to 12 years). The symptom of pain disappeared after operation. There were no evidence of recurrence. Tibial pathological fracture happened in one patient 4 months postoperatively, and the patient got healing after plate-screw internal fixation. One patient with sinus formation 5 years postoperatively got wound healing after sinus resection, intramedullary nail removal and debridement.
According to the typical clinical presentation, radiographic findings, the diagnosis of osteoid osteoma is not difficult. Once the diagnosis is confirmed, the operation should be carried out as early as possible to relieve the symptoms, improve the quality of life and prevent long-term complications.
研究骨样骨瘤的临床特点及外科治疗方法,提高其诊断与治疗水平。
回顾性分析1997年1月至2009年10月间诊治的35例骨样骨瘤患者的临床资料。其中男性25例,女性10例,平均年龄21岁(6~49岁)。症状出现至诊断的平均间隔时间为12个月(1~24个月)。最常见的发病部位为胫骨(13例)和股骨(7例)。骨样骨瘤患者最常见的症状是疼痛,通常对非甾体抗炎药有反应,且夜间一般更严重。影像学表现为圆形或椭圆形瘤巢。所有患者均接受了手术治疗。19例行刮除或切除加自体或异体骨移植,9例行单纯手术切除,7例行刮除或切除加自体或异体骨移植及内固定。
平均随访49个月(2个月至12年)。术后疼痛症状消失,无复发迹象。1例患者术后4个月发生胫骨病理性骨折,经钢板螺钉内固定后愈合。1例患者术后5年形成窦道,经窦道切除、髓内钉取出及清创后伤口愈合。
根据典型的临床表现及影像学表现,骨样骨瘤的诊断并不困难。一旦确诊,应尽早手术以缓解症状、提高生活质量并预防远期并发症。