Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.
J Dermatol. 2010 Oct;37(10):900-3. doi: 10.1111/j.1346-8138.2010.00907.x.
A case of granular cell tumor (GCT) was reported. We encountered a 33-year-old woman with a painless, elastic, hard mass in the soft tissue of the suprasternal space. The tumor was excised with several millimeters margin of normal tissue above the deep cervical fascia and the wound was closed primarily. Histological examination on hematoxylin-eosin stain showed a tumor growth in the mid- to deep dermis and eosinophilic small granules that were consistent with granular cell tumors. Immunohistochemical studies showed positive staining for S-100 protein. We experienced a case of a granular cell tumor occurring in the suprasternal space and report the importance of including it in the differential diagnosis of subcutaneous soft tissue tumors.
报告 1 例颗粒细胞瘤（GCT）。我们遇到 1 例 33 岁女性，胸骨上间隙软组织内有一无痛、弹性、硬的肿块。肿瘤在深颈筋膜上方正常组织切缘数毫米处被切除，伤口一期缝合。苏木精-伊红染色的组织学检查显示肿瘤在中至深真皮层生长，嗜酸性小颗粒与颗粒细胞瘤一致。免疫组织化学研究显示 S-100 蛋白阳性染色。我们遇到 1 例发生在胸骨上间隙的颗粒细胞瘤，并报告了将其纳入皮下软组织肿瘤鉴别诊断的重要性。
