Yang G Y
Chinese People's Liberation Army General Hospital.
Zhonghua Wai Ke Za Zhi. 1990 Dec;28(12):730-3, 782.
38 white rabbits in 4 groups were used in this experiment to investigated the metaplastic process and the outcome of the autografted periosteum on cartilage defect created artificially on acetabulum and femoral condyle. The specimens were scrupulously surveyed with conventional methods and analysis of their trace elements and amino acids, which was the means first used in evaluating the nature of metaplastic tissue. Conclusions drown from this experiment are as follows: (1) The autografted periosteum processes a metaplastic potential of forming articular cartilage under certain conditions. (2) Continuous passive movement of the grafted joint accelerate the metaplastic process, forming cartilage. (3) Synovial fluid plays certain role in survival of the transplanted periosteum and its metaplasia. However, excision of the synovium did not affect the result much, probably due to its rapid and powerful regeneration.
本实验选用38只白兔，分为4组，研究自体骨膜移植到人工造成的髋臼和股骨髁软骨缺损处后的化生过程及结果。用常规方法并通过对其微量元素和氨基酸进行分析对标本进行了细致的观察，这是首次用于评估化生组织性质的方法。从本实验得出的结论如下：（1）自体骨膜在一定条件下具有形成关节软骨的化生潜能。（2）移植关节的持续被动运动加速化生过程，形成软骨。（3）滑液在移植骨膜的存活及其化生过程中起一定作用。然而，切除滑膜对结果影响不大，可能是因为滑膜再生迅速且强大。
