Cardin G, Caporale M C, Ramuscello G, Garro R, Karavidas A, Azzolini R, Permutti B, Dalla Volta S
Cattedra di Cardiologia, Università di Padova.
G Clin Med. 1990 Dec;71(12):735-8.
A sharp and unusually high increase in the serum of glutamic-oxalacetic and glutamic-pyruvic transaminase and of lactic-dehydrogenase accompanied the terminal events, acute pulmonary edema with cardiogenic shock, in 2 patients suffering from chronic congestive heart failure caused by dilatative myocardiopathy. Experimental and clinical data raises the possibility that the considerable enzymic increase may be due to the combined effect of chronic stasis and acute ischemia on the liver.
在2例由扩张型心肌病引起的慢性充血性心力衰竭患者中,在终末期事件(急性肺水肿伴心源性休克)出现时,血清谷氨酸草酰乙酸转氨酶、谷氨酸丙酮酸转氨酶和乳酸脱氢酶急剧且异常升高。实验和临床数据提示,酶的显著升高可能是由于肝脏长期淤血和急性缺血的共同作用。