Control Group, Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK.
Biochem Soc Trans. 2010 Oct;38(5):1265-9. doi: 10.1042/BST0381265.
Bacteria are capable of sensing and responding to changes in their environment. One of the ways they do this is via chemotaxis, regulating swimming behaviour. The chemotaxis pathway senses chemoattractant gradients and uses a feedback loop to change the bacterial swimming pattern; this feedback loop differs in detail between species. In the present article, we summarize the current understanding of the regulatory mechanisms in three species and how these pathways can be viewed and analysed through the ideas of feedback control systems engineering.
细菌能够感知并对其环境变化做出反应。它们这样做的一种方式是通过趋化作用来调节游动行为。趋化作用途径感知化学引诱剂梯度,并使用反馈环改变细菌的游动模式;这种反馈环在不同物种之间存在细节差异。在本文中,我们总结了三种物种中调节机制的现有理解,以及如何通过反馈控制系统工程的思想来观察和分析这些途径。