儿童逐搏QT间期变异性：正常及生理数据
Beat-to-beat QT interval variability in children: normal and physiologic data.
作者信息
Kusuki Hirofumi, Kuriki Marina, Horio Kayo, Hosoi Misa, Matsuura Hideaki, Fujino Masayuki, Eryu Yoshihiko, Miyata Masafumi, Yasuda Toshiaki, Yamazaki Toshio, Nagaoka Shunji, Hata Tadayoshi
机构信息
Clinical Laboratory, Mie University Hospital, Japan.
出版信息
J Electrocardiol. 2011 May-Jun;44(3):326-9. doi: 10.1016/j.jelectrocard.2010.07.016. Epub 2010 Sep 21.
BACKGROUND
QT interval variability provides information on ventricular vulnerability. However, QT interval variability in children has not been adequately evaluated.
METHODS
One hundred seventy-three consecutive nursing infants and children (male-female, 106:67) up to school age with no intrinsic cardiac disease were included in this study, and they were categorized into 6 age-related groups. The QT variability index (QTVI) was calculated based on an electrocardiogram; and age-specific standard values, sex-specific classification, and a standard growth curve covering 0 to 7 years were constructed.
RESULTS
The QTVI decreased in an age-dependent manner, reached constant values after school age, and exhibited no sex-specific differences in 6 age-related groups.
CONCLUSIONS
Based on the age-dependent standardized QTVI values, it is possible to estimate the instability of ventricular repolarization in pediatric patients with better accuracy.
背景
QT间期变异性可提供关于心室易损性的信息。然而，儿童的QT间期变异性尚未得到充分评估。
方法
本研究纳入了173例无先天性心脏病的学龄以下连续护理婴儿和儿童（男女性别比为106:67），并将他们分为6个年龄相关组。基于心电图计算QT变异性指数（QTVI）；构建了0至7岁的年龄特异性标准值、性别特异性分类和标准生长曲线。
结果
QTVI呈年龄依赖性下降，学龄后达到恒定值，在6个年龄相关组中未表现出性别特异性差异。
结论
基于年龄依赖性标准化QTVI值，可以更准确地估计儿科患者心室复极的不稳定性。
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