Etienne-Mastroianni B, Girard N, Ginguene C, Tronc F, Vasiljevic A, Vallee B, Cordier J-F
Service de pneumologie, hôpital Louis-Pradel, groupement hospitalier Est, hospices civils de Lyon, BP Lyon-Montchat, 69394 Lyon cedex, France.
Rev Mal Respir. 2010 Sep;27(7):764-9. doi: 10.1016/j.rmr.2010.06.017. Epub 2010 Aug 1.
Pulmonary metastases from meningioma are rare and present with specific clinical and radiological features. The diagnostic and therapeutic management of metastatic meningioma illustrate the concept of orphan thoracic oncology.
We report the case of a 58-year-old male, former smoker, with a previous history of atypical meningioma and resected lung adenocarcinoma. During oncologic surveillance, a computed-tomography scan disclosed multiple well-defined homogeneous nodules in the right lung. These nodules were hypermetabolic at positron-emission tomography with fluorodesoxyglucose. Pathological examination of metastasectomy specimens revealed metastatic malignant meningioma.
Pulmonary metastases may occur in malignant meningioma. Twenty-one cases have been reported over the past 20 years. As for all rare tumours, multidisciplinary consensus is mandatory, in the absence of evidence-based recommendations based on prospective trials or observational studies.
脑膜瘤肺转移罕见，具有特定的临床和影像学特征。转移性脑膜瘤的诊断和治疗体现了罕见胸部肿瘤学的概念。
我们报告一例58岁男性，既往吸烟，曾患非典型脑膜瘤，已切除肺腺癌。在肿瘤监测期间，计算机断层扫描显示右肺有多个边界清晰的均匀结节。这些结节在氟脱氧葡萄糖正电子发射断层扫描中呈高代谢。转移瘤切除标本的病理检查显示为转移性恶性脑膜瘤。
恶性脑膜瘤可能发生肺转移。在过去20年中已报道21例。对于所有罕见肿瘤，在缺乏基于前瞻性试验或观察性研究的循证推荐时，多学科共识是必要的。
