Jain P, Gupta A, Sharma B K
Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Indian J Ophthalmol. 1990 Oct-Dec;38(4):169-74.
This study correlates the fundus signs with the severity and signs of hypertension and evaluates the role of fluorescein angiography in detecting changes in the retinal and choroidal capillary bed in hypertension and defines its advantages over direct ophthalmoscopy. 37 hypertensives belonging to all grades of hypertension were studied. A thorough physical examination, hypertension work up, direct ophthalmoscopy and fluorescein angiography was done in all cases. A significant association was found between the presence of marked arteriolar narrowing and the presence of severe hypertension, left ventricular hypertrophy (LVH) and cardiomegaly. Patients having definite arterio-venous crossing changes and exudative retinopathy had a higher incidence of LVH and cardiomegaly. Renal functions and neurological signs in hypertension showed no correlation with the fundus signs. Capillary bed and choriodal abnormalities could be better studied on fluorescein angiography. Hard exudates were not visualized on fluorescein angiography. There was total resolution of exudative phenomenon on treatment.
本研究将眼底征象与高血压的严重程度及体征相关联，并评估荧光素血管造影在检测高血压患者视网膜和脉络膜毛细血管床变化中的作用，同时明确其相对于直接检眼镜检查的优势。对37例不同高血压分级的高血压患者进行了研究。所有病例均进行了全面的体格检查、高血压评估、直接检眼镜检查和荧光素血管造影。发现明显的小动脉狭窄与严重高血压、左心室肥厚（LVH）和心脏扩大之间存在显著关联。有明确动静脉交叉改变和渗出性视网膜病变的患者，LVH和心脏扩大的发生率更高。高血压患者的肾功能和神经体征与眼底征象无相关性。荧光素血管造影能更好地研究毛细血管床和脉络膜异常。荧光素血管造影未显示硬性渗出。治疗后渗出现象完全消退。
