Ramaswamy Anikode S, Chatura K Ramakantha
Department of Pathology, People's Education Society Institute of Medical Sciences and Research, Kuppam, India.
Ann Saudi Med. 2011 Jan-Feb;31(1):83-6. doi: 10.4103/0256-4947.70575.
Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences are common, and late metastases have been recorded. A closely related tumor, the so-called hyalinizing spindle cell tumor with giant collagen rosettes (HSCTGR), has also been described, with both the neoplasms having a similar cytogenetic abnormality and clinical behavior. Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas. Two cases of HSCTGR occurring in the lower limb are described in this report.
低度纤维黏液样肉瘤是一种罕见的深部软组织肿瘤，显微镜下表现出看似良性的外观。在特征性黏液样基质中发现呈线性或漩涡状排列的梭形细胞，有少量或无核分裂象，这可能会造成诊断上的两难。复发很常见，并且已有晚期转移的记录。一种密切相关的肿瘤，即所谓的伴有巨大胶原玫瑰花结的透明变性梭形细胞瘤（HSCTGR）也已被描述，这两种肿瘤具有相似的细胞遗传学异常和临床行为。由于存在这些相似性，这两种病变在低度肉瘤范围内被视为单一实体。本报告描述了2例发生于下肢的HSCTGR。
