单身生活与急性心肌梗死患者的长期死亡率增加有关。
Single-living is associated with increased risk of long-term mortality among employed patients with acute myocardial infarction.
机构信息
Department of Cardiology S, Herlev University Hospital, Denmark.
出版信息
Clin Epidemiol. 2010 Aug 9;2:91-8. doi: 10.2147/clep.s8975.
Abstract
OBJECTIVE
There is conflicting evidence about the impact of social support on adverse outcome after acute myocardial infarction (MI). We examined the relation between single-living and long-term all-cause mortality after MI.
DESIGN
A prospective cohort study of 242 employed patients with MI followed up to 16 years after MI.
RESULTS
A total of 106 (43.8%) patients died during the follow-up. Single-living nearly doubled the risk of death; after adjusting for potential confounding factors, single-living was an independent predictor of death, with a hazard ratio of 2.55 (95% confidence interval: 1.52-4.30). Other predictors of death were diabetes mellitus, atrial fibrillation, age, and ejection fraction less than 35%.
CONCLUSION
Single-living is a prognostic determinant of long-term all-cause mortality after MI.
摘要
目的
关于社会支持对急性心肌梗死（MI）后不良结局的影响，目前存在相互矛盾的证据。我们研究了独居与 MI 后长期全因死亡率之间的关系。
设计
一项前瞻性队列研究，对 242 名有工作的 MI 患者进行随访，随访时间长达 16 年。
结果
共有 106 名（43.8%）患者在随访期间死亡。独居使死亡风险几乎增加了一倍；在调整了潜在的混杂因素后，独居是死亡的独立预测因素，其危险比为 2.55（95%置信区间：1.52-4.30）。其他死亡预测因素包括糖尿病、心房颤动、年龄和射血分数<35%。
结论
独居是 MI 后长期全因死亡率的预后决定因素。
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