Abteilung Zelluläre und Molekulare Immunologie, Zentrum für Hygiene und Humangenetik, Humboldtallee 34, Göttingen, Germany.
Semin Thromb Hemost. 2010 Sep;36(6):611-9. doi: 10.1055/s-0030-1262882. Epub 2010 Sep 23.
Modern, that is, accurate determination of complement activation in vivo requires the simultaneous determination of both naive and activated complement proteins. This is best achieved by the use of native-restricted and neoepitope-specific monoclonal antibodies in sensitive enzyme-linked immunosorbent assays. Several confounding factors also have to be taken into account to allow a correct interpretation of the results.
现代的，也就是，准确地确定体内补体激活需要同时测定天然和激活的补体蛋白。这最好通过在敏感的酶联免疫吸附测定中使用天然限制和新表位特异性单克隆抗体来实现。为了正确解释结果，还必须考虑到几个混杂因素。
