Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, PR China.
J Sep Sci. 2010 Oct;33(20):3159-67. doi: 10.1002/jssc.201000030.
Ionic liquid (IL) stationary phase is especially suitable for separation of complex samples, owing to the "dual nature" of IL. In this study, a synthetic method of ionic liquid-bonded polysiloxane (PSOIL) as stationary phase of GC was proposed. Then, the PSOIL was used to prepare an 8 m capillary column by static method. The column efficiency was measured to be about 4000 plates/m (k=3.55, naphthalene) after the column had been conditioned at 210°C. The durability of PSOIL column was better than that of the mixed stationary phase of IL and OV-1. Moreover, the Abraham solvation parameter model was employed to characterize the PSOIL. The result revealed that the PSOIL had stronger dispersion force (l) than neat IL and stronger hydrogen bond basicity (a) than DB-1. That meant the PSOIL might offer good selectivity for both polar and non-polar analytes. The column exhibited unique selectivity for various organic substances, such as the homologous compounds of alkanes, esters, alcohols and aromatic compounds. It was also found that some aromatic positional isomers could be separated better on the PSOIL column than on the DB-1 column. Furthermore, the stationary phase was suitable for separation of high-boiling point compounds such as polycyclic aromatic hydrocarbons, phthalic esters, etc. All of these demonstrated that the PSOIL offered good selectivity and high separation efficiency for a wide range of analytes.
离子液体（IL）固定相特别适合于复杂样品的分离，这归因于 IL 的“双重性质”。在本研究中，提出了一种离子液体键合聚硅氧烷（PSOIL）作为 GC 固定相的合成方法。然后，通过静态法将 PSOIL 用于制备 8 m 长的毛细管柱。在 210°C 下对柱进行条件处理后，测得柱效率约为 4000 板/m（k=3.55，萘）。PSOIL 柱的耐用性优于 IL 和 OV-1 的混合固定相。此外，采用 Abraham 溶剂化参数模型对 PSOIL 进行了表征。结果表明，PSOIL 比纯 IL 具有更强的色散力（l），比 DB-1 具有更强的氢键碱性（a）。这意味着 PSOIL 可能对极性和非极性分析物都具有良好的选择性。该柱对各种有机物质具有独特的选择性，例如烷烃、酯、醇和芳香族化合物的同系物。还发现一些芳香族位置异构体在 PSOIL 柱上比在 DB-1 柱上能更好地分离。此外，该固定相适用于分离高沸点化合物，如多环芳烃、邻苯二甲酸酯等。所有这些都表明 PSOIL 对广泛的分析物具有良好的选择性和高分离效率。
