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瑞芬太尼输注用于小儿支气管镜下异物取出术:七氟醚与丙泊酚用于支气管镜插入麻醉补充的比较

Remifentail infusion for paediatric bronchoscopic foreign body removal: comparison of sevoflurane with propofol for anaesthesia supplementation for bronchoscope insertion.

作者信息

Zhang J, Wang Y, Li B, Zhang W

机构信息

Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Anaesth Intensive Care. 2010 Sep;38(5):905-10. doi: 10.1177/0310057X1003800431.

Abstract

The study compared sevoflurane or propofol as anaesthesia supplements to remifentanil infusion and topical local anaesthesia for insertion of a rigid bronchoscope for bronchial foreign body removal in children aged one to three years. Seventy children were randomly allocated to two groups to receive remifentanil infusion at 0.2 microg x kg(-1) x min(-1) with either sevoflurane or propofol supplements for insertion of the rigid bronchoscope. Heart rate and systolic blood pressure before anaesthesia, prior to and on insertion of the bronchoscope and one, three, five, seven and ten minutes after insertion were measured. Incidence of cough and apnoea were recorded. The haemodynamic changes during bronchoscopy were moderate and did not differ between groups. The sevoflurane group had a lower incidence of cough than the propofol group. No significant difference was detected in the incidence of apnoea between groups. It can be concluded that remifentanil infusion with modest use of general anaesthetic agents facilitates rigid bronchoscopy successfully in children.

摘要

该研究比较了七氟醚或丙泊酚作为瑞芬太尼输注及局部表面麻醉的补充,用于1至3岁儿童插入硬质支气管镜以取出支气管异物的情况。70名儿童被随机分为两组,在插入硬质支气管镜时接受0.2微克/千克/分钟的瑞芬太尼输注,并分别用七氟醚或丙泊酚作为补充。测量麻醉前、插入支气管镜前及插入时、插入后1、3、5、7和10分钟时的心率和收缩压。记录咳嗽和呼吸暂停的发生率。支气管镜检查期间的血流动力学变化适中,两组之间无差异。七氟醚组的咳嗽发生率低于丙泊酚组。两组之间呼吸暂停的发生率未检测到显著差异。可以得出结论,适度使用全身麻醉剂的瑞芬太尼输注有助于儿童成功进行硬质支气管镜检查。

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