• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脂质双分子层膜在熔点转变时的离子通道样行为。

Ion-channel-like behavior in lipid bilayer membranes at the melting transition.

作者信息

Gallaher Jill, Wodzińska Katarzyna, Heimburg Thomas, Bier Martin

机构信息

Department of Physics, East Carolina University, Greenville, North Carolina 27858, USA.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6 Pt 1):061925. doi: 10.1103/PhysRevE.81.061925. Epub 2010 Jun 30.

DOI:10.1103/PhysRevE.81.061925
PMID:20866458
Abstract

It is well known that at the gel-liquid phase-transition temperature a lipid bilayer membrane exhibits an increased ion permeability. We analyze the quantized currents in which the increased permeability presents itself. The open time histogram shows a "-3/2" power law which implies an open-closed transition rate that decreases like k(t)∝t(-1) as time evolves. We propose a "pore freezing" model to explain the observations. We discuss how this model also leads to the 1/fα noise that is commonly observed in currents across biological and artificial membranes.

摘要

众所周知,在凝胶 - 液相转变温度下,脂质双分子层膜表现出离子渗透性增加。我们分析了渗透率增加时出现的量子化电流。开放时间直方图显示出“-3/2”幂律,这意味着随着时间的推移,开闭转换速率像k(t)∝t(-1)一样下降。我们提出了一个“孔冻结”模型来解释这些观察结果。我们讨论了这个模型如何也导致了在生物膜和人工膜电流中普遍观察到的1/fα噪声。

相似文献

1
Ion-channel-like behavior in lipid bilayer membranes at the melting transition.脂质双分子层膜在熔点转变时的离子通道样行为。
Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6 Pt 1):061925. doi: 10.1103/PhysRevE.81.061925. Epub 2010 Jun 30.
2
Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.溶血脂掺入二棕榈酰磷脂酰胆碱双层膜中可增强膜相变时的离子渗透性和药物释放速率。
Biochim Biophys Acta. 2005 Oct 15;1716(2):77-96. doi: 10.1016/j.bbamem.2005.08.007. Epub 2005 Sep 7.
3
Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations.利用分子动力学模拟估算脂质双层液晶相和凝胶相中电穿孔的活化能及孔生长速率。
Soft Matter. 2015 Nov 28;11(44):8632-40. doi: 10.1039/c5sm02029h.
4
Modified Donnan potentials for ion transport through biological ion channels.通过生物离子通道进行离子运输的修正唐南电位。
Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jun;63(6 Pt 1):061902. doi: 10.1103/PhysRevE.63.061902. Epub 2001 May 21.
5
Lattice model for the kinetics of rupture of fluid bilayer membranes.流体双层膜破裂动力学的晶格模型
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 May;67(5 Pt 1):051908. doi: 10.1103/PhysRevE.67.051908. Epub 2003 May 14.
6
Resealing dynamics of a cell membrane after electroporation.电穿孔后细胞膜的重新封闭动力学
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Dec;66(6 Pt 1):062905. doi: 10.1103/PhysRevE.66.062905. Epub 2002 Dec 26.
7
A DSC and FTIR spectroscopic study of the effects of the epimeric 4-cholesten-3-ols and 4-cholesten-3-one on the thermotropic phase behaviour and organization of dipalmitoylphosphatidylcholine bilayer membranes: comparison with their 5-cholesten analogues.DSC 和 FTIR 光谱研究差向异构体 4-胆甾烯-3-醇和 4-胆甾烯-3-酮对二棕榈酰磷脂酰胆碱双层膜热致相态行为和组织的影响:与 5-胆甾烯类似物的比较。
Chem Phys Lipids. 2014 Jan;177:71-90. doi: 10.1016/j.chemphyslip.2013.11.008. Epub 2013 Dec 1.
8
A model for self-sustained potential oscillation of lipid bilayer membranes induced by the gel-liquid crystal phase transitions.一种由凝胶 - 液晶相变诱导的脂质双分子层膜自持电位振荡模型。
Biophys J. 1993 May;64(5):1461-75. doi: 10.1016/S0006-3495(93)81513-3.
9
Permeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisited.芳香族羧酸跨脂质双层的渗透:重新审视pH分配假说。
Biophys J. 2005 Sep;89(3):1802-11. doi: 10.1529/biophysj.105.060871. Epub 2005 Jun 10.
10
[A soft poration of planar bilayer lipid membranes from dipalmitoylphosphatidylcholine at the temperature of the phase transition from the liquid crystalline to the gel state].[在从液晶态到凝胶态的相变温度下,由二棕榈酰磷脂酰胆碱形成的平面双层脂质膜的软穿孔]
Biofizika. 2005 Sep-Oct;50(5):867-77.

引用本文的文献

1
Nanoparticle-based optical interfaces for retinal neuromodulation: a review.用于视网膜神经调节的基于纳米颗粒的光学界面:综述
Front Cell Neurosci. 2024 Mar 20;18:1360870. doi: 10.3389/fncel.2024.1360870. eCollection 2024.
2
Thermal damage threshold of neurons during infrared stimulation.红外刺激期间神经元的热损伤阈值。
Biomed Opt Express. 2020 Mar 27;11(4):2224-2234. doi: 10.1364/BOE.383165. eCollection 2020 Apr 1.
3
Erlang flow of hydrophilic pore formation and closure events in a lipid bilayer during phase transition resulting from diffusion in the radius space.
在相变过程中,由于半径空间中的扩散导致脂质双层中亲水性孔形成和关闭事件的埃尔朗流。
Eur Biophys J. 2018 Apr;47(3):297-307. doi: 10.1007/s00249-017-1261-3. Epub 2017 Oct 25.
4
The Effect of the Nonlinearity of the Response of Lipid Membranes to Voltage Perturbations on the Interpretation of Their Electrical Properties. A New Theoretical Description.脂质膜对电压扰动响应的非线性对其电学性质解释的影响。一种新的理论描述。
Membranes (Basel). 2015 Sep 25;5(4):495-512. doi: 10.3390/membranes5040495.
5
Photoactivation of neurons by laser-generated local heating.通过激光产生的局部加热对神经元进行光激活。
AIP Adv. 2012 Aug 23;2(3):032154. doi: 10.1063/1.4748955. eCollection 2012 Sep.
6
Liquid general anesthetics lower critical temperatures in plasma membrane vesicles.液体全身麻醉剂降低质膜囊泡中的临界温度。
Biophys J. 2013 Dec 17;105(12):2751-9. doi: 10.1016/j.bpj.2013.11.005.
7
Lytic and non-lytic permeabilization of cardiolipin-containing lipid bilayers induced by cytochrome C.细胞色素 C 诱导含心磷脂的脂质双层的溶解和非溶解通透化
PLoS One. 2013 Jul 22;8(7):e69492. doi: 10.1371/journal.pone.0069492. Print 2013.
8
Voltage-Gated Lipid Ion Channels.电压门控脂质离子通道
PLoS One. 2013 Jun 18;8(6):e65707. doi: 10.1371/journal.pone.0065707. Print 2013.
9
The stability of solitons in biomembranes and nerves.生物膜和神经中孤子的稳定性。
Eur Phys J E Soft Matter. 2011 Jun;34(6):57. doi: 10.1140/epje/i2011-11057-0. Epub 2011 Jun 9.
10
A lipocentric view of peptide-induced pores.以脂肪为中心的肽诱导孔观点。
Eur Biophys J. 2011 Apr;40(4):399-415. doi: 10.1007/s00249-011-0693-4. Epub 2011 Mar 26.