Division of Cardiology, The Heart Institute at Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45244, USA.
Heart Fail Clin. 2010 Oct;6(4):531-58, ix-x. doi: 10.1016/j.hfc.2010.06.001.
Although pediatric heart failure is generally a chronic, progressive disorder, recovery of ventricular function may occur with some forms of cardiomyopathy. Guidelines for the management of chronic heart failure in adults and children have recently been published by the International Society for Heart and Lung Transplantation the American College of Cardiology, and the American Heart Association. The primary aim of heart failure therapy is to reduce symptoms, preserve long-term ventricular performance, and prolong survival primarily through antagonism of the neurohormonal compensatory mechanisms. Because some medications may be detrimental during an acute decompensation, physicians who manage these patients as inpatients must be knowledgeable about the medications and therapeutic goals of chronic heart failure treatment. Understanding the mechanisms of chronic heart failure may foster improved understanding of the treatment of decompensated heart failure.
虽然儿科心力衰竭通常是一种慢性、进行性疾病,但某些形式的心肌病可能会出现心室功能的恢复。国际心肺移植学会、美国心脏病学会和美国心脏协会最近发布了成人和儿童慢性心力衰竭管理指南。心力衰竭治疗的主要目的是通过拮抗神经激素代偿机制来减轻症状、保持长期心室功能并延长生存时间。由于某些药物在急性失代偿期间可能有害,因此管理这些患者的住院医师必须了解慢性心力衰竭治疗的药物和治疗目标。了解慢性心力衰竭的机制可能有助于更好地理解失代偿性心力衰竭的治疗。