Laboratorio de Fenómenos No Lineales, Escuela de Física, Facultad de Ciencias, Universidad Central de Venezuela, Caracas, Venezuela.
Med Eng Phys. 2010 Dec;32(10):1131-6. doi: 10.1016/j.medengphy.2010.08.004. Epub 2010 Sep 24.
Results of a comparative analysis between Heart Rate (HR) patterns occurring before the onset of Paroxysmal Ventricular Tachycardia (PVT) and from healthy subjects are shown. Two study groups were made after electrocardiographic dynamical monitoring (Holter) of volunteers. The first group includes 100h from 27 healthy control subjects, and the second group consists of 88h, ending with self-terminating episodes of PVT from 55 patients. Patterns are defined as sequences of consecutive RR intervals, while atypical patterns are defined as corresponding to unlikely behavior of Heart Rate in healthy subjects. We investigated spatial and temporal distributions of these patterns in order to find early signs of PVT. We found that they can be grouped on a reduced number of clusters, and the number of atypical patterns increases as we approach the onset of the episode.
展示了在阵发性室性心动过速 (PVT) 发作前出现的心率 (HR) 模式与健康受试者的心率模式之间的对比分析结果。在对志愿者进行心电图动态监测 (动态心电图) 后,分成了两个研究组。第一组包括 27 名健康对照者的 100 小时,第二组包括 88 小时,最后是 55 名患者的自行终止的 PVT 发作。模式被定义为连续 RR 间隔的序列,而不典型模式则被定义为对应于健康受试者中 HR 不太可能的行为。我们调查了这些模式的时空分布,以寻找 PVT 的早期迹象。我们发现,它们可以分为少数几个簇,而且随着发作的临近,不典型模式的数量会增加。