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转移性指骨溶骨性病变,作为结肠癌的初始表现。

Metastatic phalangeal osteolysis as an initial presentation of carcinoma colon.

机构信息

Department of Medicine, Kottayam Medical College, Kerala, India.

出版信息

Am J Surg. 2010 Nov;200(5):e61-3. doi: 10.1016/j.amjsurg.2010.02.016. Epub 2010 Sep 27.

DOI:10.1016/j.amjsurg.2010.02.016
PMID:20870210
Abstract

Metastatic malignancies of the hand are rare and usually develop from lung, breast, or kidney tumors. Metastases from tumors and sarcomas of the gastrointestinal system are even more uncommon. The authors report a case of differentiated adenocarcinoma of the colon in a 76-year-old man who presented with distal phalangeal metastasis and osteolysis in the form of a painful swelling at the tip of the right little finger of 6 months duration. Computed tomography of the abdomen and colonoscopy revealed a mass in the transverse colon. Diagnosis was confirmed by biopsy. Treatment was given with palliative local radiation and systemic chemotherapy. After 4 weeks of chemotherapy, the patient discontinued treatment and eventually succumbed to the disease.

摘要

手部转移性恶性肿瘤较为罕见,通常由肺癌、乳腺癌或肾癌转移而来。胃肠道系统肿瘤和肉瘤的转移更为少见。作者报告了一例 76 岁男性患者的结肠分化腺癌病例,该患者因右手小指远端指骨转移和骨质溶解而出现疼痛性肿胀,病程长达 6 个月。腹部和结肠镜检查显示横结肠有肿块。通过活检确诊。采用姑息性局部放疗和全身化疗进行治疗。化疗 4 周后,患者停止治疗,最终死于该疾病。

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