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职业性接触油雾后脂质性肺炎病例中石蜡的气相色谱/质谱检测

GC/MS detection of paraffins in a case of lipoid pneumonia following occupational exposure to oil spray.

作者信息

Penes M C, Vallon J J, Sabot J F, Vallon C

机构信息

Laboratoire de Biochimie et Toxicologie, Hopital Edouard Herriot, Lyon, France.

出版信息

J Anal Toxicol. 1990 Nov-Dec;14(6):372-4. doi: 10.1093/jat/14.6.372.

Abstract

A case of lipoid pneumonia following occupational exposure to oil spray is described. Biological fluids (broncho-alveolar lavage and pleural fluid) are analyzed to determine if the compounds found in the industrial oils are present. The samples are purified using high-performance thin-layer chromatography, and after extraction, the compounds were submitted to infrared spectroscopy. Direct hexane extraction of biological fluids is also performed, followed by gas chromatography/mass spectrometry (GC/MS).

摘要

本文描述了一例因职业接触油雾引发的类脂性肺炎病例。对生物体液(支气管肺泡灌洗和胸腔积液)进行分析,以确定工业用油中发现的化合物是否存在。样品通过高效薄层色谱法进行纯化,提取后,对这些化合物进行红外光谱分析。还对生物体液进行了直接正己烷萃取,随后进行气相色谱/质谱联用(GC/MS)分析。

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