Department of Dental Science, University of Trieste, 34127 Trieste, Italy.
J Oncol. 2010;2010. doi: 10.1155/2010/202305. Epub 2010 Sep 1.
Lymphoproliferative disorders are heterogeneous malignancy characterized by the expansion of a lymphoid clone more or less differentiated. At the level of the oral cavity, the lymphoproliferative disorder can occur in various ways, most commonly as lymphoid lesions with extranodal externalization, but sometimes, oral lesions may represent a localization of a disease spread. With regard to the primary localizations of lymphoproliferative disorders, a careful examination of the head and neck, oral, and oropharyngeal area is necessary in order to identify suspicious lesions, and their early detection results in a better prognosis for the patient. Numerous complications have been described and frequently found at oral level, due to pathology or different therapeutic strategies. These complications require precise diagnosis and measures to oral health care. In all this, oral pathologists, as well as dental practitioners, have a central role in the treatment and long-term monitoring of these patients.
淋巴增生性疾病是一种异质性恶性肿瘤,其特征是淋巴细胞克隆或多或少地分化。在口腔水平,淋巴增生性疾病可以以各种方式发生,最常见的是伴结外外显的淋巴病变,但有时,口腔病变可能代表疾病播散的局部定位。关于淋巴增生性疾病的原发性定位,需要仔细检查头颈部、口腔和口咽区域,以识别可疑病变,早期发现可改善患者预后。由于病理或不同的治疗策略,已描述并经常在口腔水平发现许多并发症。这些并发症需要对口腔健康护理进行精确的诊断和措施。在这一切中,口腔病理学家以及牙科医生在这些患者的治疗和长期监测中发挥着核心作用。