Lotrich Francis
Department of Psychiatry, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.
Curr Hepat Rep. 2010 Apr 6;9(2):113-118. doi: 10.1007/s11901-010-0035-5.
Depression and other influences on mental health can impact antiviral response rates during chronic hepatitis C treatment, the quality of life for these patients, and the risk for adverse outcomes such as suicide. Enhanced treatment outcomes for patients who are receiving interferon-α requires 1) addressing preexisting mental health problems, 2) alleviating psychiatric conditions that emerge during treatment, and 3) prediction and prevention of these conditions. Accumulating evidence indicates that these three goals are feasible. Collaborative involvement of psychiatric management may often be critical in this regard.
抑郁症及其他对心理健康的影响,会在慢性丙型肝炎治疗期间影响抗病毒反应率、这些患者的生活质量以及诸如自杀等不良后果的风险。提高接受α-干扰素治疗患者的治疗效果需要:1)解决已有的心理健康问题;2)缓解治疗期间出现的精神状况;3)预测和预防这些状况。越来越多的证据表明这三个目标是可行的。在这方面,精神科管理的协作参与往往至关重要。