适体诱导的近红外发光铂（II）三联吡啶配合物的自组装用于无标记和固定化检测溶菌酶和凝血酶。
Aptamer-induced self-assembly of a NIR-emissive platinum(II) terpyridyl complex for label- and immobilization-free detection of lysozyme and thrombin.
机构信息
Institute of Molecular Functional Materials (Areas of Excellence Scheme, University Grants Committee, Hong Kong) and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.
出版信息
Chem Commun (Camb). 2010 Nov 7;46(41):7709-11. doi: 10.1039/c0cc02631j. Epub 2010 Sep 24.
PMID:20871876
Abstract
With the aptamer-induced self-assembly feature of NIR-emissive platinum(ii) terpyridyl complex, a "proof-of-principle" concept in label- and immobilization-free probing strategies of lysozyme and thrombin has been demonstrated with good selectivity and specificity.
摘要
基于近红外发光的铂（ii）-三联吡啶配合物的适体诱导自组装特性，本文展示了一种无需标记和固定化的溶菌酶和凝血酶探测策略的“原理验证”概念，具有良好的选择性和特异性。
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