Huber M, Jennes H W, Bamborschke S
Klinik und Poliklinik für Neurologie, Universität Köln.
Med Klin (Munich). 1990 Dec 15;85(12):696-9.
Although intensive care medicine and chemotherapy of bacterial infections have made great progress during the last 30 years, therapeutic efficacy in bacterial meningitis in adult patients could not be improved. Retrospective analysis of 391 cases of adult bacterial meningitis between 1950 and 1985 shows no significant changes in etiology and only slight reduction in mortality. The course of the disease depends mostly on age, state of consciousness and CSF cell count. Cases of meningitis in HIV patients and cerebral tuberculosis have not been evaluated in this study.
尽管在过去30年中，重症监护医学和细菌感染化疗取得了巨大进展，但成年患者细菌性脑膜炎的治疗效果仍未能得到改善。对1950年至1985年间391例成年细菌性脑膜炎病例的回顾性分析表明，病因没有显著变化，死亡率仅略有下降。疾病的病程主要取决于年龄、意识状态和脑脊液细胞计数。本研究未评估艾滋病患者和脑结核患者的脑膜炎病例。
