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溶栓联合球囊扩张治疗门静脉血栓可使活体肝移植后成功进行抗病毒治疗:病例报告。

A combination procedure with thrombolytic therapy and balloon dilatation for portal vein thrombus enables the successful performance of antiviral therapy after a living-donor liver transplantation: report of a case.

机构信息

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

出版信息

Surg Today. 2010 Oct;40(10):986-9. doi: 10.1007/s00595-009-4159-6. Epub 2010 Sep 25.

DOI:10.1007/s00595-009-4159-6
PMID:20872206
Abstract

This report presents a case of portal vein thrombosis possibly caused by anastomotic stricture after living-donor liver transplantation. The patient underwent systemic thrombolytic therapy with tissue plasminogen activator and subsequent balloon dilatation of the stenotic lesion, and both were successful. These procedures allowed the patient to receive antiviral therapy to improve the pancytopenia, leading to a sustained virological response.

摘要

本报告介绍了一例活体肝移植后吻合口狭窄可能导致门静脉血栓形成的病例。患者接受了组织型纤溶酶原激活物全身溶栓治疗和随后的狭窄病变球囊扩张治疗,均获得成功。这些治疗措施使患者能够接受抗病毒治疗以改善全血细胞减少症,从而获得持续的病毒学应答。

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本文引用的文献

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Surg Today. 2009;39(5):367-73. doi: 10.1007/s00595-008-3917-1. Epub 2009 Apr 30.
2
Portal vein complications after adult-to-adult living donor liver transplantation.成人活体肝移植术后门静脉并发症
Transpl Int. 2008 Dec;21(12):1136-44. doi: 10.1111/j.1432-2277.2008.00752.x. Epub 2008 Sep 1.
3
Evolution of living donor liver transplantation over 10 years: experience of a single center.活体肝移植10年发展历程:单中心经验
Surg Today. 2008;38(9):795-800. doi: 10.1007/s00595-007-3729-8. Epub 2008 Aug 28.
4
Portal vein complications in pediatric living donor liver transplantation using left-side grafts.
Am J Transplant. 2008 Oct;8(10):2097-105. doi: 10.1111/j.1600-6143.2008.02360.x. Epub 2008 Aug 22.
5
Intentional conversion from tacrolimus to cyclosporine for HCV-positive patients on preemptive interferon therapy after living donor liver transplantation.对于活体供肝移植后接受抢先性干扰素治疗的丙型肝炎病毒阳性患者,将他克莫司有意转换为环孢素。
Ann Transplant. 2007;12(4):11-5.
6
Clearance of hepatitis C virus after living-donor liver transplantation in spite of residual viremia on end date of interferon therapy before transplantation.尽管在移植前干扰素治疗结束时仍存在残余病毒血症,但活体肝移植后丙型肝炎病毒清除。
World J Gastroenterol. 2007 Aug 14;13(30):4149-51. doi: 10.3748/wjg.v13.i30.4149.
7
Early posttransplantation portal vein stenosis following living donor liver transplantation: percutaneous transhepatic primary stent placement.活体肝移植术后早期门静脉狭窄:经皮肝穿刺原发性支架置入术
Liver Transpl. 2007 Apr;13(4):530-6. doi: 10.1002/lt.21068.
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Role of interventional radiology in the management of vascular complications after liver transplantation.介入放射学在肝移植术后血管并发症管理中的作用。
Transplant Proc. 2004 Apr;36(3):552-4. doi: 10.1016/j.transproceed.2004.02.038.
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