Yang Wen-Zeng, Cui Zhen-Yu, Zhang Wei, Zhou Hong-Yue, Wang Quan-Sheng, Zhang Yan-Qiao, Shi Xiao-Qiang
Department of Urology, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, China.
Zhonghua Nan Ke Xue. 2010 Jul;16(7):627-30.
To explore the clinical value and safety of TRUS-guided transperineal biopsy with the 9 + X method in the diagnosis of prostate carcinoma.
A total of 420 men underwent TRUS-guided transperineal biopsy with the 9 + X method for suspected prostate carcinoma. Their clinical data were retrospectively analyzed.
Prostate carcinoma was detected in 160 (38.1%) of the 420 cases, accounting for 7.4%, 17.8% and 65.4% in those with PSA < 4.0 microg/L, 4 -10 microg/L and > 10 microg/L respectively, 25.0% in those with abnormal findings on digital rectal examination (DRE), and 22.2% in those with abnormal echoes on TRUS or abdominal ultrasound examination. Complications after prostatic biopsy included gross hematuria in 79 cases (18.8%), acute urinary retention in 13 (3.1%) and fever in 9 (2.1%), but no other serious complications were observed.
TRUS-guided transperineal biopsy with the 9 + X method, with high accuracy and fewer complications, is an ideal approach to the diagnosis of prostate carcinoma.
探讨经直肠超声（TRUS）引导下9 + X法经会阴前列腺穿刺活检在前列腺癌诊断中的临床价值及安全性。
对420例疑似前列腺癌患者采用TRUS引导下9 + X法经会阴前列腺穿刺活检，回顾性分析其临床资料。
420例患者中，160例（38.1%）确诊为前列腺癌，前列腺特异性抗原（PSA）<4.0μg/L、4 - 10μg/L、>10μg/L患者中前列腺癌的检出率分别为7.4%、17.8%、65.4%，直肠指检（DRE）异常者中前列腺癌检出率为25.0%，经直肠超声或腹部超声检查回声异常者中前列腺癌检出率为22.2%。前列腺穿刺活检术后并发症包括肉眼血尿79例（18.8%）、急性尿潴留13例（3.1%）、发热9例（2.1%），未观察到其他严重并发症。
TRUS引导下9 + X法经会阴前列腺穿刺活检诊断前列腺癌准确性高，并发症少，是一种理想的诊断方法。
