Hirota S, Sako M, Hase M, Sugimoto K, Fujita Y, Ogasawara M, Nagae T, Fujii M, Kono M
Department of Radiology, Kobe University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1990 Nov 25;50(11):1448-50.
To improve distribution of drug by intraarterial infusion a new catheter system with sideholes, tip of which was able to be occluded by an embolus, was developed. Inner diameter of the catheter was 0.038 inch. Tip of the catheter was so smoothly tapered to 0.025 inch in inner diameter that it could be occluded by an embolus of 0.038 inch in diameter. After occlusion of the tip, drug flowed out rectangly to catheter axis from only sideholes, resulting that drug flowed out was mixtured by blood stream to make a uniform distribution of it.
为了通过动脉内灌注改善药物分布，研发了一种带有侧孔的新型导管系统，其尖端能够被栓子阻塞。导管的内径为0.038英寸。导管尖端内径平滑地逐渐变细至0.025英寸，以至于它可以被直径为0.038英寸的栓子阻塞。尖端阻塞后，药物仅从侧孔呈矩形流向导管轴，结果流出的药物与血流混合，使其分布均匀。
