Suppr超能文献

支架置入术治疗大肠梗阻可避免造口:连续 100 例患者的系列研究。

Stenting large bowel obstruction avoids a stoma: consecutive series of 100 patients.

机构信息

Department of Colorectal Surgery, Royal Prince Alfred Hospital, New South Wales, Australia.

出版信息

Colorectal Dis. 2011 Oct;13(10):1138-41. doi: 10.1111/j.1463-1318.2010.02432.x.

Abstract

AIM

Large bowel obstruction (LBO) is a surgical emergency that requires urgent operative intervention and often a stoma. The introduction of a self-expanding metallic stent provides an alternative for this group of patients. The aim of this study was to assess prospectively the results in the first 100 consecutive patients with LBO undergoing attempted self-expanding metallic stent insertion at the Royal Prince Alfred Hospital, Sydney, Australia.

METHOD

A prospective consecutive uncontrolled trial of 100 patients having an attempted self-expanding metallic stent insertion for LBO was performed after institutional ethical approval.

RESULTS

The mean age was 63.9 years (range 16-95). Primary colorectal cancer was the most common cause of LBO (61%). A self-expanding metallic stent was inserted with a palliative intent in 89% of patients. An initial technical success rate of 87% was achieved. Overall 30-day mortality was 7% (95% CI, 3.4-13.7%), with only one stent-related death within 30 days of stent insertion. Morbidity occurred in 20% of patients. Surgery was avoided in 69 patients and permanent stoma was avoided in 72 patients. The median follow up was 34.5 months (range 1-64 months).

CONCLUSION

In this uncontrolled study, self-expanding metallic stents had a low morbidity and a low procedure-related mortality. A randomized controlled trial has commenced in our institution, in which length of stay, quality of life, morbidity and mortality of patients with stents are compared with those of patients having open procedures during palliative care for LBO.

摘要

目的

大肠梗阻(LBO)是一种需要紧急手术干预的外科急症,通常需要造口术。自膨式金属支架的引入为这组患者提供了另一种选择。本研究旨在前瞻性评估 100 例连续 LBO 患者在澳大利亚悉尼皇家阿尔弗雷德王子医院接受自膨式金属支架置入术的结果。

方法

对 100 例接受 LBO 自膨式金属支架置入术的患者进行了一项机构伦理批准后的前瞻性连续非对照试验。

结果

平均年龄为 63.9 岁(范围 16-95 岁)。原发性结直肠癌是 LBO 最常见的原因(61%)。89%的患者以姑息为目的插入自膨式金属支架。初始技术成功率为 87%。总体 30 天死亡率为 7%(95%CI,3.4-13.7%),仅 1 例支架相关死亡发生在支架置入后 30 天内。20%的患者发生了并发症。69 例患者避免了手术,72 例患者避免了永久性造口术。中位随访时间为 34.5 个月(范围 1-64 个月)。

结论

在这项非对照研究中,自膨式金属支架的发病率和与手术相关的死亡率较低。我们的机构已经开始了一项随机对照试验,其中比较了支架患者与接受姑息性 LBO 开放手术患者的住院时间、生活质量、发病率和死亡率。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验