难治性抑郁症研究中的方法学问题。
Methodological problems in treatment resistant depression research.
作者信息
Nierenberg A A
机构信息
Treatment Resistant Depression Program, McLean Hospital, Harvard Medical School, Belmont, MA 02178.
出版信息
Psychopharmacol Bull. 1990;26(4):461-4.
PMID:2087540
Abstract
To better understand why treatment resistant depression (TRD) has been resistant to systematic study, the author analyzes methodologic problems facing TRD researchers with a focus on the difficulty of defining TRD. Then approaches for clinicians to interpret limited and potentially biased TRD data are suggested.
摘要
为了更好地理解为什么难治性抑郁症（TRD）一直难以进行系统研究，作者分析了TRD研究人员面临的方法学问题，重点关注TRD定义的困难。然后提出了临床医生解释有限且可能有偏差的TRD数据的方法。
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