Holoye P Y, Samuels M L, Smith T, Sinkovics J G
Cancer. 1978 Jul;42(1):34-40. doi: 10.1002/1097-0142(197807)42:1<34::aid-cncr2820420106>3.0.co;2-8.
Thirty-one patients with small cell bronchogenic carcinoma were treated with a regimen of cyclophosphamide, Adriamycin and vincristine. Radiotherapy was given to patients with limited disease. Nonspecific immunotherapy consisting of BCG scarification was administered after each chemotherapy course. The results of treatment for this group were compared with those for a group of 45 patients treated similarly but with no immunotherapy. Therapeutic results, expressed in length of survival and rate of response, were similar. Myelosuppression was not modified by the addition of BCG scarification. This study showed no benefit from the use of such nonspecific immunotherapy.
31例小细胞支气管癌患者接受了环磷酰胺、阿霉素和长春新碱方案的治疗。对病变局限的患者进行了放疗。在每个化疗疗程后给予由卡介苗划痕组成的非特异性免疫治疗。将该组的治疗结果与另一组45例接受类似治疗但未进行免疫治疗的患者的结果进行了比较。以生存期和缓解率表示的治疗结果相似。添加卡介苗划痕并未改变骨髓抑制情况。该研究表明使用这种非特异性免疫治疗并无益处。
