Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, Florida 33136, USA.
Arthroscopy. 2010 Dec;26(12):1641-7. doi: 10.1016/j.arthro.2010.03.019. Epub 2010 Sep 27.
The purpose of this study was to evaluate the initial biomechanical properties of a fan-folded, single-loop construct of fan-folded fascia lata allograft in comparison to other graft tissues currently being used for anterior cruciate ligament (ACL) reconstruction.
Eighteen fascia lata specimens were harvested from 11 donors and fan folded through a proprietary process. Bone-patellar tendon-bone (BPTB), tibialis anterior, tibialis posterior, and peroneus longus tendons were harvested from 4 additional donors. All soft-tissue grafts were tested to failure in an MTS machine (MTS Systems, Eden Prairie, MN) in a single-looped fashion. BPTB grafts were similarly clamped in freeze grips. The ultimate load to failure and stiffness were calculated for each graft type tested.
The mean ultimate load to failure was 3,266 N and stiffness was 414 N/mm for the single-looped fascia lata grafts (n = 18). There was no significant difference for ultimate load to failure and stiffness between the fascia lata and tibialis anterior (3,012 N and 342 N/mm, respectively), tibialis posterior (3,666 N and 392 N/mm, respectively), and peroneus longus (3,050 N and 346 N/mm, respectively) tendons. The fascia lata grafts performed significantly better (P < .001) than BPTB (1,404 N and 224 N/mm, respectively).
A single-loop construct of fan-folded fascia lata allograft has, on biomechanical testing, initial ultimate tensile strength (3,266 N) and stiffness values equivalent to or better than several other graft tissues currently used in ACL reconstruction, including BPTB (1,403 N), tibialis anterior (3,012 N), tibialis posterior (3,666 N), and peroneus longus (3,050 N).
In the face of potential allograft tissue shortages and increasing constraints on health care expenditures, the use of fascia lata has the potential to be a readily available graft for ACL reconstruction that performs as well as other grafts and at a comparable or lower cost.
本研究旨在评估折叠扇形、单环结构的折叠扇形阔筋膜同种异体移植物的初始生物力学特性,并将其与目前用于前交叉韧带(ACL)重建的其他移植物组织进行比较。
从 11 名供体中采集了 18 个阔筋膜标本,并通过专利工艺折叠。从另外 4 名供体中采集了髌腱-骨(BPTB)、胫骨前肌、胫骨后肌和腓骨长肌肌腱。所有软组织移植物均在 MTS 机器(MTS Systems,Eden Prairie,MN)中以单环方式进行失效测试。BPTB 移植物也类似地用冷冻夹固定。计算每种测试移植物类型的最终失效载荷和刚度。
单环折叠阔筋膜移植物的平均最终失效载荷为 3266N,刚度为 414N/mm(n=18)。阔筋膜与胫骨前肌(分别为 3012N 和 342N/mm)、胫骨后肌(分别为 3666N 和 392N/mm)和腓骨长肌(分别为 3050N 和 346N/mm)肌腱的最终失效载荷和刚度无显著差异。阔筋膜移植物的性能明显优于 BPTB(分别为 P<0.001),后者的最终失效载荷和刚度分别为 1404N 和 224N/mm。
在生物力学测试中,折叠扇形阔筋膜同种异体移植物的单环结构具有与目前用于 ACL 重建的几种其他移植物组织(包括 BPTB(1403N)、胫骨前肌(3012N)、胫骨后肌(3666N)和腓骨长肌(3050N)相当或更好的初始极限拉伸强度(3266N)和刚度值。
在潜在的同种异体组织短缺和医疗保健支出不断增加的情况下,阔筋膜的使用有可能成为一种现成的 ACL 重建移植物,其性能与其他移植物相当,成本或更低。