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吞咽机制的声学建模。

Acoustical modeling of swallowing mechanism.

机构信息

Department of Electrical and Computer Engineering,University of Manitoba, Winnipeg, MB R3T 5V6, Canada.

出版信息

IEEE Trans Biomed Eng. 2011 Jan;58(1):81-7. doi: 10.1109/TBME.2010.2080677. Epub 2010 Sep 27.

Abstract

In this paper, a mathematical modeling of the swallowing sound generation is presented. To evaluate the model, its application on swallowing disorder (dysphagia) diagnosis is discussed. As a starting point, a simple linear time invariant model is assumed to represent the pharyngeal wall and tissue excited by a train of impulses. The modeling is approached by two different assumptions. In one approach, it is assumed that the impulse train, representing the neural activities to trigger swallow, is the same for both groups of control and dysphagic, and it is the pharyngeal model that accounts for the difference between the two groups. On the other hand, in the second approach, it is assumed that the pharyngeal response is the same for both groups, but the neural activities to initiate the swallow are different between the two groups. The results show that the second approach complies better with the physiological characteristics of swallowing mechanism as it provides a much better discrimination between the swallowing sounds of control and dysphagic groups of this study. Though, it should be noted that our dysphagic group subjects were cerebral palsy and stroke patients. Hence, the model accounting for initiation of neural activities is reasonable to show better results.

摘要

本文提出了一种吞咽声音产生的数学模型。为了评估该模型,讨论了其在吞咽障碍(吞咽困难)诊断中的应用。作为一个起点,假设一个简单的线性时不变模型来表示由一系列脉冲激励的咽壁和组织。该模型通过两种不同的假设来逼近。在一种方法中,假设代表触发吞咽的神经活动的脉冲序列对于对照组和吞咽困难组是相同的,并且是咽模型解释了两组之间的差异。另一方面,在第二种方法中,假设咽的反应对于两组是相同的,但是两组之间引发吞咽的神经活动是不同的。结果表明,第二种方法更符合吞咽机制的生理特征,因为它在控制组和吞咽困难组的吞咽声音之间提供了更好的区分。不过,应该注意的是,我们的吞咽困难组受试者是脑瘫和中风患者。因此,考虑到神经活动的启动,该模型能够得到更好的结果。

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