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[人工耳蜗:组织学数据]

[Cochlear implants: histological data].

作者信息

Fayad J, Linthicum F H, House W F

机构信息

House Ear Institute, Los Angeles, California 90057.

出版信息

Rev Laryngol Otol Rhinol (Bord). 1990;111(5):439-42.

PMID:2087606
Abstract

We have performed a histological examination of the pars petrosa of 13 implanted patients. Morphological data were confronted with the clinical findings. The results of this study show that the nerve elements stimulated by the electrode are the cells of the spiral ganglion, and that a small number of ganglionic cells, as few as 10% of the normal figure, is compatible with auditory perception by electrical stimulation. Furthermore, all the implanted pars petrosa were the seat of a fibrosis and neo-ossification reaction around and sometimes even beyond the tip of the electrode. The trauma caused by the insertion of the electrode into the cochlea involved the sensorial cells of the organ of Corti and the dendritic populations in the lamina spiralis, but the cells of the spiral ganglion were spared. Prolonged electrical stimulation (14 years in 1 case) does not appear to have any deleterious effect on the survival of the spiral ganglion, of the cochlear nerve or of the cochlear nucleus.

摘要

我们对13例植入患者的岩部进行了组织学检查。将形态学数据与临床发现进行了对比。本研究结果表明,电极刺激的神经元件是螺旋神经节细胞,少量的神经节细胞,低至正常数量的10%,与电刺激听觉感知是相符的。此外,所有植入的岩部均存在电极尖端周围甚至有时超出电极尖端范围的纤维化和新骨化反应。电极插入耳蜗所造成的创伤累及了柯蒂氏器的感觉细胞和螺旋板中的树突群体,但螺旋神经节细胞未受影响。长时间电刺激(1例为14年)似乎对螺旋神经节、耳蜗神经或耳蜗核的存活没有任何有害影响。

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