Walter Ward Consultancy and Training, Buxton, Derbyshire SK179AZ, UK.
Protein Eng Des Sel. 2011 Jan;24(1-2):65-7. doi: 10.1093/protein/gzq065. Epub 2010 Sep 27.
For several decades, the Fersht laboratory has been a world leader in research on protein structure and mechanism. There are pressing medical and financial needs for new medicines. Here, I use examples to illustrate how drug discovery could be more successful if it increased utilisation of approaches from the Fersht laboratory.
几十年来,Fersht 实验室一直是蛋白质结构和机制研究的世界领导者。新药的研发具有紧迫的医疗和财务需求。在这里,我将举例说明,如果增加使用 Fersht 实验室的方法,药物发现可能会更加成功。