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性发育障碍(DSD)的手术挑战。

The surgical challenges of disorders of sex development (DSD).

作者信息

Gorduza Daniela, Vidal Isabelle, Birraux Jacques, Gay Claire-Lise, Demède Delphine, Mure Pierre-Yves, Mouriquand Pierre

机构信息

Department of Paediatric Urology, Hôspital Mère-Enfant, Groupement Hospitalier Est, Bron, France.

出版信息

Arch Esp Urol. 2010 Sep;63(7):495-504.

Abstract

Disorders of Sex Development (DSD) remain a fascinating challenge for the paediatricians, endocrinologists, biologists, psychiatrists, geneticists, radiologists, surgeons and for the whole society. This article aims at highlighting the current controversies and questions met with genital reconstruction in children born with abnormal genitalia. The main current techniques of masculinization and feminization are reviewed with their progress and their problems. The tools of decision used to assign a gender in some newborns with complex DSD are discussed showing that at the dawn of the third millenium, one still does not know why a boy is a boy, and a girl is a girl.

摘要

性发育障碍(DSD)对于儿科医生、内分泌学家、生物学家、精神科医生、遗传学家、放射科医生、外科医生以及整个社会来说,仍然是一个极具吸引力的挑战。本文旨在突出在患有生殖器异常的儿童进行生殖器重建时遇到的当前争议和问题。回顾了当前主要的男性化和女性化技术及其进展和问题。讨论了用于为一些患有复杂DSD的新生儿指定性别的决策工具,结果表明在第三个千年伊始,人们仍然不知道为什么男孩是男孩,女孩是女孩。

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