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男性乳腺浸润性小叶癌:一种罕见疾病中的罕见组织学类型

Invasive Lobular Carcinoma of the Male Breast: A Rare Histology in an Uncommon Disease.

作者信息

Briest Susanne, Vang Russell, Terrell Kyle, Emens Leisha, R Lange Julie

机构信息

Department of Gynecology and Obstetrics, University of Leipzig, Germany.

出版信息

Breast Care (Basel). 2009;4(1):36-38. doi: 10.1159/000190078. Epub 2009 Feb 20.

Abstract

SUMMARY

BACKGROUND: Breast cancer in men is an uncommon disease. Nearly all cases of male breast cancer originate in the terminal ductulolobular unit, with exceedingly rare reports of lobular carcinoma in men. Invasive lobular cancer is found in no more than 1-2% of male breast cancer cases. Most of what is known about this disease is in the form of approximately 30 case reports in the literature. CASE REPORT: We report the case of a 52-year-old man who presented at our institution with a lump in his left breast. Ultrasound-guided biopsy revealed an invasive lobular cancer. The rare histological type was confirmed by the result of the histological examination of the mastectomy specimen. The treatment was completed by dose dense chemotherapy, radiation, and endocrine therapy. CONCLUSION: Even though lobular structures are quite infrequent in the normal male, sporadic cases of invasive lobular breast cancer have been described. A short overview will be given in this case report.

摘要

摘要

背景:男性乳腺癌是一种罕见疾病。几乎所有男性乳腺癌病例都起源于终末导管小叶单位,男性小叶癌的报道极为罕见。浸润性小叶癌在男性乳腺癌病例中所占比例不超过1%-2%。关于这种疾病的大多数认知都来自文献中约30例病例报告。病例报告:我们报告一例52岁男性患者,因左侧乳房肿块前来我院就诊。超声引导下活检显示为浸润性小叶癌。乳房切除标本的组织学检查结果证实了这种罕见的组织学类型。治疗采用剂量密集化疗、放疗和内分泌治疗。结论:尽管正常男性中小叶结构相当少见,但仍有散发性浸润性小叶乳腺癌病例的报道。本病例报告将对此进行简要概述。

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本文引用的文献

1
Male Breast Cancer.男性乳腺癌
Breast Care (Basel). 2008;3(3):183-189. doi: 10.1159/000136825. Epub 2008 Jun 24.
2
Breast Cancer in Special Situations.特殊情况下的乳腺癌
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Am J Gastroenterol. 1998 Feb;93(2):231-3. doi: 10.1111/j.1572-0241.1998.00231.x.

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