Faculdade de Ciências Médicas de Pernambuco, Universidade de Pernambuco, Recife, Brasil.
Cad Saude Publica. 2010 Sep;26(9):1693-704. doi: 10.1590/s0102-311x2010000900003.
A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban population of all Brazilian state capitals and the Federal District, between 2005 and 2009. This paper describes the design and methodology of the study which involved a population aged 5 to 19 for hepatitis A and 10 to 69 for hepatitis B and C. Interviews and blood samples were obtained through household visits. The sample was selected using stratified multi-stage cluster sampling and was drawn with equal probability from each domain of study (region and age-group). Nationwide, 19,280 households and ~31,000 residents were selected. The study is large enough to detect prevalence of viral infection around 0.1% and risk factor assessments within each region. The methodology seems to be a viable way of differentiating between distinct epidemiological patterns of hepatitis A, B and C. These data will be of value for the evaluation of vaccination policies and for the design of control program strategies.
一项基于人群的调查于 2005 年至 2009 年在巴西所有州首府和联邦区的城市人群中进行，旨在提供有关肝炎病毒感染流行情况和危险因素模式的信息。本文描述了该研究的设计和方法学，该研究涉及年龄在 5 至 19 岁的甲型肝炎人群和年龄在 10 至 69 岁的乙型和丙型肝炎人群。通过家访获取访谈和血样。使用分层多阶段聚类抽样选择样本，并从每个研究领域（地区和年龄组）以相等的概率抽取样本。在全国范围内，选择了 19280 户家庭和约 31000 名居民。该研究的规模足以检测到 0.1%左右的病毒感染流行率以及每个地区的危险因素评估。该方法似乎是区分甲型、乙型和丙型肝炎不同流行病学模式的可行方法。这些数据将有助于评估疫苗接种政策和制定控制项目策略。
