Xavier Márcia Arruda Fajardo, Ceneviva Reginaldo, Terra Filho João, Sankarankutty Ajith Kumar
Department of Surgery and Anatomy, Faculty of Medicine of Ribeirao Preto, University Hospital, USP, Sao Paulo, Brazil.
Acta Cir Bras. 2010 Oct;25(5):407-15. doi: 10.1590/s0102-86502010000500005.
To investigate the body weight, pulmonary function and quality of life of twenty patients with morbid obesity six months after the Fobi-Capella operation.
Patients were evaluated before and six months after surgery. The patients were mainly female (75%), the average age was 40.5 ± 10.27 years; average weight 110.11 kg ± 21.77 and average body mass index (BMI) 39.93 ± 7.13 kg/m² in the postoperative evaluation. Pulmonary function was assessed by spirometry using a Pulmonet/Godart NV Bilt Vetr Hotland spirometer and quality of life was assessed by applying the Moorehead-Ardelt questionnaire. The pre- and postoperative spirometry values were compared by the paired Student t test and the correlation between weight loss and pulmonary function was determined by linear regression, with the level of significance set at p < 0.05.
The spirometry variables Respiratory Frequency (RF), Expiratory Reserve Volume (ERV) and Functional Residual Capacity (FRC) differed significantly between the pre- and postoperative periods, whereas Residual Volume (RV), Vital Capacity (VC), Total Lung Capacity (TLC), FEF25-75 (Forced Expiratory Flow between 25 and 75% FVC) and FEV1/FVC% (Forced Expiratory Volume in the 1st second/ Forced Vital Capacity ratio) did not differ between periods. Only one patient reported worsening of quality of life. There was a positive correlation between weight loss and ERV (p=0.0117, r=0.5514), but no correlations were observed for the other variables.
There was a significant weight loss and an improvement of pulmonary function as seen by respiratory frequency, reduction and increased expiratory reserve volume and functional residual capacity. The quality of life of the patients also improved after the Fobi-Capella operation.
研究20例病态肥胖患者在接受福比 - 卡佩拉手术6个月后的体重、肺功能和生活质量。
对患者在手术前和术后6个月进行评估。患者主要为女性(75%),术后评估时平均年龄为40.5±10.27岁;平均体重110.11 kg±21.77,平均体重指数(BMI)为39.93±7.13 kg/m²。使用Pulmonet/Godart NV Bilt Vetr Hotland肺活量计通过肺活量测定法评估肺功能,并应用穆尔黑德 - 阿德尔问卷评估生活质量。术前和术后肺活量测定值通过配对学生t检验进行比较,体重减轻与肺功能之间的相关性通过线性回归确定,显著性水平设定为p < 0.05。
肺活量测定变量呼吸频率(RF)、呼气储备量(ERV)和功能残气量(FRC)在术前和术后期间有显著差异,而残气量(RV)、肺活量(VC)、肺总量(TLC)、FEF25 - 75(用力呼气流量在25%至75% FVC之间)和FEV1/FVC%(第1秒用力呼气量/用力肺活量比值)在各期间无差异。只有1例患者报告生活质量恶化。体重减轻与ERV之间存在正相关(p = 0.0117,r = 0.5514),但其他变量未观察到相关性。
福比 - 卡佩拉手术后患者体重显著减轻,肺功能得到改善,表现为呼吸频率降低、呼气储备量和功能残气量增加。患者的生活质量也有所改善。