Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung County, Taiwan.
Surg Obes Relat Dis. 2011 Sep-Oct;7(5):599-604. doi: 10.1016/j.soard.2011.04.221. Epub 2011 Apr 19.
Obesity is associated with impaired pulmonary function. We evaluated the effect of bariatric surgery on pulmonary function among obese patients and identified potential anthropometric factors of obesity corresponding to the reversal of impaired pulmonary function.
Pulmonary function and anthropometric factors were studied in 94 obese patients aged 18-65 years with a body mass index >32 kg/m(2). Pulmonary function tests were performed preoperatively and 3 months after bariatric surgery. The measurements included forced vital capacity (FVC), forced expiratory volume in the first second (FEV(1)), total lung capacity, expiratory reserve volume, residual volume, and diffusing capacity of the lung for carbon monoxide. The anthropometric factors included the body weight, body mass index, waist circumference (WC), hip circumference, waist/height ratio, and waist/hip ratio. The changes in anthropometric parameters were analyzed in relation to pulmonary function test results. Multiple linear regression models were applied to identify the factors that influenced pulmonary function after bariatric surgery.
When measured 3 months after surgery, all anthropometric parameters for the 94 patients studied had significantly decreased, and the pulmonary function test parameters had significantly improved. Of the anthropometric parameters, the reduction in body weight, WC, and waist/height ratio correlated significantly with increases in the FEV(1) and FVC. In the multiple linear regression analysis, only the reduction in WC correlated significantly with the reductions in the FEV(1) and FVC.
After bariatric surgery, all anthropometric parameters of obesity decreased significantly and the pulmonary function improved. This improvement correlated best with the reduction in the WC and perhaps a decreased intra-abdominal pressure.
肥胖与肺功能受损有关。我们评估了减重手术对肥胖患者肺功能的影响，并确定了肥胖的潜在人体测量学因素与肺功能受损的逆转相对应。
研究了 94 名年龄在 18-65 岁、体重指数（BMI）>32kg/m²的肥胖患者的肺功能和人体测量学因素。在减重手术前和术后 3 个月进行肺功能测试。测量包括用力肺活量（FVC）、第 1 秒用力呼气量（FEV1）、肺总量、呼气储备量、残气量和一氧化碳弥散量。人体测量学因素包括体重、BMI、腰围（WC）、臀围、腰高比和腰臀比。分析了人体测量参数的变化与肺功能测试结果的关系。应用多元线性回归模型来确定减重手术后影响肺功能的因素。
术后 3 个月测量时，94 例患者的所有人体测量参数均显著降低，肺功能测试参数显著改善。在人体测量学参数中，体重、WC 和腰高比的降低与 FEV1 和 FVC 的增加显著相关。多元线性回归分析中，仅 WC 的降低与 FEV1 和 FVC 的降低显著相关。
减重手术后，肥胖的所有人体测量学参数均显著降低，肺功能得到改善。这种改善与 WC 的降低以及可能的腹内压降低相关性最好。
