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使用多排螺旋计算机断层扫描评估先天性心脏病患儿改良布莱洛克-陶西格分流术

Assessment of modified Blalock-Taussig shunt in children with congenital heart disease using multidetector-row computed tomography.

作者信息

Nabo Manal Mohamed Helmy, Hayabuchi Yasunobu, Inoue Miki, Watanabe Noriko, Sakata Miho, Kagami Shoji

机构信息

Department of Pediatrics, University of Tokushima, Kuramoto-cho-3, Tokushima 770-8503, Japan.

出版信息

Heart Vessels. 2010 Nov;25(6):529-35. doi: 10.1007/s00380-010-0007-2. Epub 2010 Sep 28.

Abstract

The purpose of this study was to assess the feasibility of multidetector-row computed tomography (MDCT) for the evaluation of modified Blalock-Taussig (B-T) shunt in children with congenital heart disease associated with reduced pulmonary blood flow. A total of 25 consecutive patients (mean age, 2.6 ± 3.6 years; range, 2 months-16 years) underwent MDCT angiography of the thorax with a 16-detector row scanner prior to cardiac catheterization. A total of 39 shunts (right, 22; left, 17) were included in the study. Conventional angiographic findings were used as the gold standard for the detection of B-T shunts. Shunt diameter was measured quantitatively and independently at four sites (the subclavian artery site, the pulmonary artery site, the widest site, and the stenotic site) on MDCT and on conventional invasive angiography. All B-T shunts were depicted on multiplanar reconstruction (MPR), maximum intensity projection (MIP), curved planar reconstruction (CPR), and three-dimensional volume-rendered (VR) images, enabling evaluation in all patients except for one with occluded shunt. There were excellent correlations between MDCT- and conventional angiography-based measurements of shunt diameter at the subclavian artery site, pulmonary artery site, and the widest site (R² = 0.46, 0.74 and 0.64, respectively; p < 0.0001 for each), although systematic overestimation was observed for MDCT (mean percentage of overestimation, 23.1 ± 32.4%). Stenotic site diameter and degree of stenosis showed a mild correlation (R² = 010 and 0.25, respectively; p < 0.01 for each). This study demonstrates that MDCT is a promising tool for the detection of lesions in B-T shunts.

摘要

本研究的目的是评估多排螺旋计算机断层扫描(MDCT)用于评估先天性心脏病合并肺血流减少患儿改良布莱洛克-陶西格(B-T)分流术的可行性。共有25例连续患者(平均年龄2.6±3.6岁;范围2个月至16岁)在心脏导管检查前行16排螺旋扫描仪胸部MDCT血管造影。本研究共纳入39个分流术(右侧22个;左侧17个)。传统血管造影结果用作检测B-T分流术的金标准。在MDCT和传统有创血管造影上,在四个部位(锁骨下动脉部位、肺动脉部位、最宽部位和狭窄部位)定量且独立地测量分流直径。所有B-T分流术均在多平面重建(MPR)、最大密度投影(MIP)、曲面平面重建(CPR)和三维容积再现(VR)图像上显示,除1例分流闭塞患者外,所有患者均可进行评估。在锁骨下动脉部位、肺动脉部位和最宽部位,基于MDCT和传统血管造影测量的分流直径之间存在极好的相关性(R²分别为0.46、0.74和0.64;各p<0.0001),尽管MDCT存在系统性高估(平均高估百分比为23.1±32.4%)。狭窄部位直径和狭窄程度显示出轻度相关性(R²分别为0.10和0.25;各p<0.01)。本研究表明,MDCT是检测B-T分流术病变的一种有前景的工具。

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