Interaction of DNA with nuclear skeleton in rat hepatocytes.
作者信息
Widłak P, Rogoliński J, Rzeszowska-Wolny J
机构信息
Institute of Oncology, Department of Tumour Biology, Gliwice, Poland.
出版信息
Acta Biochim Pol. 1990;37(1):69-72.
PMID:2087918
Abstract
We have characterized fractions liberated from rat liver cell nuclei digested with DNase I and treated with buffers containing 0.1, 0.5 and 2 M NaCl. Analysis of DNA and proteins present in these fractions as well as in nuclear matrix, confirms the chromatin model according to which transcriptionally active loops interact differently with nuclear skeleton than inactive ones.
摘要
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