Karnik Vaishali V, Fenster Aaron, Bax Jeff, Gardi Lori, Gyacskov Igor, Montreuil Jacques, Romagnoli Cesare, Ward Aaron D
Biomedical Engineering Graduate Program, The University of Western Ontario, London, ON, Canada N6A 5C1.
Med Image Comput Comput Assist Interv. 2010;13(Pt 2):17-25. doi: 10.1007/978-3-642-15745-5_3.
To ensure accurate targeting and repeatability, 3D TRUS-guided biopsies require registration to determine coordinate transformations to (1) incorporate pre-procedure biopsy plans and (2) compensate for inter-session prostate motion and deformation between repeat biopsy sessions. We evaluated prostate surface- and image-based 3D-to-3D TRUS registration by measuring the TRE of manually marked, corresponding, intrinsic fiducials in the whole gland and peripheral zone, and also evaluated the error anisotropy. The image-based rigid and non-rigid methods yielded the best results with mean TREs of 2.26 mm and 1.96 mm, respectively. These results compare favorably with a clinical need for an error of less than 2.5 mm.
为确保准确靶向和可重复性,三维经直肠超声引导下的活检需要进行配准,以确定坐标变换,从而(1)纳入术前活检计划,以及(2)补偿重复活检期间不同检查之间前列腺的运动和变形。我们通过测量整个腺体和外周区手动标记的、对应的、内在基准点的配准误差(TRE),评估了基于前列腺表面和图像的三维到三维经直肠超声配准,并评估了误差各向异性。基于图像的刚性和非刚性方法产生了最佳结果,平均配准误差分别为2.26毫米和1.96毫米。这些结果与小于2.5毫米的误差临床需求相比具有优势。