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兔自体睫毛玻璃体异物的磁敏感加权成像特征分析

Characteristic analysis on susceptibility weighted imaging of intravitreous foreign body of autologous eyelashes in rabbits.

作者信息

Yang Yun-jun, Cheng Jing-liang, Wang Juan, Zhang Yong, Li Hua-li

机构信息

MRI Division, Department of Radiology, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

出版信息

Chin J Traumatol. 2010 Oct 1;13(5):304-7.

PMID:20880458
Abstract

OBJECTIVE

To explore the characteristics of susceptibility weighted imaging (SWI) of the intravitreous foreign body of autologous eyelashes in rabbits.

METHODS

A total of 12 New Zealand white rabbits, either sex, weighing 2.5-3.5 kg, and provided by the Experimental Animal Center of Henan Province were employed in this study. For each rabbit, 5 autologous eyelashes (1 cm in length and 0.2-0.3 mm in diameter) were implanted into the right ocular vitreum, while the left control ocular vitreum received sham operation but nothing was implanted. SWI sequential test was made 2 hours postoperatively. Then the rabbits were killed and the specimens of the vitreous bodies of the rabbits were obtained. Hematoxylin and eosin staining and histological examinations were performed.

RESULTS

The autologous eyelashes in 8 ocular vitreums of rabbits showed linear low signal intensity on the magnitude images and susceptibility weighted images, but linear high signal intensity on the phase images. Among the 12 experimental rabbits, 5 eyelashes in the right vitreum were completely shown in 3 rabbits, partly shown in 5 rabbits (2 eyelashes shown in 3 rabbits and 3 eyelashes shown in 2 rabbits), and not shown in 4 rabbits.

CONCLUSIONS

SWI of the foreign body of intravitreous autologous eyelashes in rabbits has its own characteristics. The combined application of SWI sequential magnitude images, susceptibility weighted images and phase images is helpful to the detection and diagnosis of intravitreous autologous eyelashes in rabbits.

摘要

目的

探讨兔自体睫毛玻璃体异物的磁敏感加权成像(SWI)特征。

方法

本研究采用河南省实验动物中心提供的12只新西兰白兔,雌雄不限,体重2.5 - 3.5 kg。每只兔将5根自体睫毛(长度1 cm,直径0.2 - 0.3 mm)植入右眼玻璃体,左眼作为对照眼行假手术,不植入任何东西。术后2小时行SWI序列检查。然后处死兔子,获取兔玻璃体标本,进行苏木精-伊红染色及组织学检查。

结果

兔8只眼玻璃体中的自体睫毛在幅值图像和磁敏感加权图像上呈线状低信号强度,但在相位图像上呈线状高信号强度。12只实验兔中,3只兔右眼玻璃体中的5根睫毛完全显示,5只兔部分显示(3只兔显示2根睫毛,2只兔显示3根睫毛),4只兔未显示。

结论

兔自体睫毛玻璃体异物的SWI有其自身特点。SWI序列幅值图像、磁敏感加权图像和相位图像联合应用有助于兔自体睫毛玻璃体异物的检测与诊断。

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