Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON.
Curr Oncol. 2010 Sep;17 Suppl 2(Suppl 2):S38-44. doi: 10.3747/co.v17i0.698.
The discovery of androgen deprivation therapy (ADT) has been one of the most important advances in the treatment of prostate cancer. Here, the indications for the use of ADT are reviewed, together with the data supporting each indication. The settings for ADT use include cytoreduction; combined ADT and radiotherapy; pathologic node-positive disease; and recurrent, metastatic, or progressive prostate cancer.
雄激素剥夺疗法 (ADT) 的发现是前列腺癌治疗中最重要的进展之一。本文回顾了 ADT 的适应证,并介绍了支持每种适应证的数据。ADT 的应用场景包括细胞减灭术;联合 ADT 和放疗;病理淋巴结阳性疾病;以及复发性、转移性或进展性前列腺癌。