Division of Urology, Department of Surgery, McGill University, Montreal, QC.
Curr Oncol. 2010 Sep;17 Suppl 2(Suppl 2):S65-71. doi: 10.3747/co.v17i0.722.
The diagnosis and treatment of prostate cancer have steadily been improving since the late 1980s. However, clinicians still confront a large group of men developing disease metastatic to bone. Adequate control of bone complications plays a fundamental role in achieving control of symptoms and quality of life in this group. Androgen deprivation therapy, the standard treatment for advanced prostate cancer, increases the risk of various complications, including bone disease. This review addresses the prevention of bone complications related not only to prostate cancer metastases but also to impaired bone integrity caused by androgen deprivation therapy.
自 20 世纪 80 年代末以来，前列腺癌的诊断和治疗一直在稳步改善。然而，临床医生仍然面临着一大群发生骨转移疾病的男性。充分控制骨并发症对于控制这组患者的症状和生活质量起着至关重要的作用。雄激素剥夺疗法是晚期前列腺癌的标准治疗方法，会增加各种并发症的风险，包括骨疾病。本综述不仅涉及与前列腺癌转移相关的骨并发症的预防，还涉及雄激素剥夺治疗引起的骨完整性受损的预防。
