1,8 - 二羟基 - 9 - 蒽酮（地蒽酚）在吡啶中自氧化产生的自由基中间体。
Free radical intermediates produced by autoxidation of 1,8-dihydroxy-9-anthrone (dithranol) in pyridine.
作者信息
Martinmaa J, Vanhala L, Mustakallio K K
出版信息
Experientia. 1978 Jul 15;34(7):872-3. doi: 10.1007/BF01939674.
PMID:208855
Abstract
The autoxidation of the antipsoriatic agent dithranol, monitored by an ESR-spectrometer, proceeds through several free radical intermediates. The initial radical, attacking a bulky spin trapping agent in a sterically comparatively hindered constellation, may be the active therapeutic form of dithranol.
摘要
通过电子自旋共振光谱仪监测，抗银屑病药物地蒽酚的自动氧化过程会产生几种自由基中间体。最初的自由基在空间位阻相对较大的环境中攻击一种体积较大的自旋捕获剂，它可能是地蒽酚的活性治疗形式。
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